In this paper, we propose a novel, secure, and intelligent IoT approach based on agent, we have implemented in the health care domain, where we developed an intelligent patient monitoring system for monitoring the patients heart rate automatically. Our system is more intelligent that can anticipate the critical condition before it even happens, send a message to the patient family, doctors, nurses, as well as hospital in-charge personal, and launch an alarm to be assisted by the nearest people in place. Also, our architecture ensures the authentication, authorization, and data sensing confidentiality. Hospitals and medical clinics can utilize our system to monitor their outpatients who are in danger of unpredictable health conditions. The approach presented in the paper can also be applied to other IoT domains.