<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>10</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kermiche,Boubaker</style></author><author><style face="normal" font="default" size="100%">Mohamed-Ridha  Guedjati</style></author><author><style face="normal" font="default" size="100%">Naouel Chibout</style></author><author><style face="normal" font="default" size="100%">Salah Ferhi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Influence des qualités rédactionnelles des QCM sur la performance des étudiants : étude analytique d&amp;rsquo;une banque de 150 QCM type A de physiologie </style></title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%"> https://doi.org/10.1051/pmed/2016014</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>10</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kermiche,Boubaker</style></author><author><style face="normal" font="default" size="100%">Naouel Chibout</style></author><author><style face="normal" font="default" size="100%">Guedjati,Mouhamed-Ridha</style></author><author><style face="normal" font="default" size="100%">Salah Ferhi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comment contrer les obstacles de la communication en pédagogie des sciences de la santé ?</style></title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%"> https://doi.org/10.1051/pmed/2016012</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohamed Ridha Guedjati</style></author><author><style face="normal" font="default" size="100%">Kermiche,Boubaker</style></author><author><style face="normal" font="default" size="100%">Naouel Chibout</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Implanter une évaluation par des stations d&amp;rsquo;examen clinique objectif structuré(ECOS) en phase prédoctorale dans une faculté de médecine Algérienne. Obstacles et pistes de solutions </style></title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://doi.org/10.1051/pmed/2016014</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Khaled,M</style></author><author><style face="normal" font="default" size="100%">G Belaaloui</style></author><author><style face="normal" font="default" size="100%">Jiang,Z.-Z.</style></author><author><style face="normal" font="default" size="100%">Zhu,X</style></author><author><style face="normal" font="default" size="100%">Zhang,L.-Y</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antitumor effect of Deoxypodophyllotoxin on human breast cancer xenograft transplanted in BALB/c nude mice model.</style></title></titles><dates><year><style  face="normal" font="default" size="100%">2016</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/27578026</style></url></web-urls></urls><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;
	Recently, biologically active compounds isolated from plants used in herbal medicine have been the center of interest. Deoxypodophyllotoxin (DPT), structurally closely related to the lignan podophyllotoxin, was found to be a potent antitumor and antiproliferative agent, in several tumor cells, in vitro. However, DPT has not been used clinically yet because of the lack of in vivo studies. This study is the first report demonstrating the antitumor effect of DPT on MDA-MB-231 human breast cancer xenografts in nude mice. DPT, significantly, inhibited the growth of MDA-MB-231 xenograft in BALB/c nude mice. The T/C value (the value of the relative tumor volume of treatment group compared to the control group) of groups treated with 5, 10, and 20 mg/kg of intravenous DPT-HP-β-CD was 42.87%, 34.04% and 9.63%, respectively, suggesting the positive antitumor activity of DPT. In addition, the antitumor effect of DPT-HP-β-CD (20 mg/kg) in human breast cancer MDA-MB-231 xenograft was more effective than etoposide (VP-16) (20 mg/kg) and docetaxel (20 mg/kg). These findings suggest that this drug is a promising chemotherapy candidate against human breast carcinoma.
&lt;/p&gt;
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